government site. as well as many foods. Hi! It is an organic compound commonly found in topical corticosteroids (CS). Patch testing detailsAmerican Contact Dermatitis Core Series: 30% aqueous solutionNZ Extended Series: 5% petrolatum. 2021 Jun;67(6):414-419. doi: 10.46747/cfp.6706414. Propylene glycol is also found in oral treatments Before Disclaimer, National Library of Medicine doi:10.1097/DER.0000000000000315. polypropylene vs propylene glycol On 5th November 2022 / samsung connect to pc software This site needs JavaScript to work properly. [1] The site is secure. Contact allergy to topical glucocorticoids. government site. Among the patients we patch tested, propylene glycol was found to be the contactant in a majority of cases, not the minoxidil itself. An official website of the United States government. Propylene glycol allergic contact dermatitis. Research has suggested that individuals who have a sensitivity to propylene glycol may experience a special form of irritation known as allergic contact dermatitis. Dela J Public Health. 2005 Nov;53(5):247-59. doi: 10.1111/j.0105-1873.2005.00693.x. The most common side effect of topical minoxidil is irritant contact dermatitis with the typical symptoms of itching and scaling. 2015 Nov-Dec;32(6):e242-4. HHS Vulnerability Disclosure, Help Their chemical formula is HO (CH2 CH2) OH. Saudi Med J. Survivorship-Reducing Effect of Propylene Glycol on Vector Mosquito Populations and Its Potential Use in Attractive Toxic Sugar Baits. The allergy medicine companies didn't respond back when we emailed to ask the source of the ingredients. Signs you have a propylene glycol allergy Your skin will itch, burn, and feel tender Your scalp may feel dry, and flake You can develop a red rash on your hairline, ear, or neck Your skin will feel swollen The symptoms appear one to two days after you come in contact with the allergen Dermatol Clin. Ingredients. Positive patch-test reactions to propylene glycol: a retrospective cross-sectional analysis from the North American Contact Dermatitis Group, 1996 to 2006. Your patch test result indicates that you have a contact allergy to propylene glycol. The https:// ensures that you are connecting to the Most commonly, these symptoms are a result of an allergic reaction to propylene glycol, or less commonly, to minoxidil itself. My skin problems, however, go back to June 2013 when I was misdiagnosed with "postmenopausal atrophic vaginitis". It causes contact dermatitis and also systemic contact dermatitis, meaning if you have a skin allergy to propylene glycol, it may also cause a reaction if you inhale it or are exposed to it orally, in an injection, or through the mucosa (mouth . You may need to check with your pharmacist or doctor which topical and other medications will be suitable for you. Accessibility Propylene glycol is a widely used emollient and emulsifier with well-established irritant and allergic potential. Before Kidney and liver toxicity. This is characterised by a rash, possibly with small lumps in the surrounding area or even just a patch of redness. Approche de la dermatite de contact allergique cause par les mdicaments topiques. Can Fam Physician. "Propylene glycol is often the culprit." It may also be employed as a preservative, and is extensively used in foods and cosmetics ( 1 ). Books about skin diseasesBooks about the skin 2018 Jun;120(6):599-602. doi: 10.1016/j.anai.2018.04.017. Because PG is inhaled when you vape, this will be around your mouth and nose. DermNet does not provide an online consultation service.If you have any concerns with your skin or its treatment, see a dermatologist for advice. 2018;29(1):612. Cutaneous reactions to PG are mostly irritant, but allergic contact dermatitis to PG is well-documented. bacitracin or neomycin sulfate. Review of Allergic Contact Dermatitis ACD is an immunological reaction that occurs in genetically susceptible people who have been previously sensitized to an allergen. and transmitted securely. These rashes are not contagious or life-threatening, but can be very uncomfortable. This is one of the first ingredients IN EVERYTHING - shampoo, the best foundations, cleansers, deodorant, toothpaste, even donuts. "If you are developing a red, itchy rash where you're applying your product, you may have an allergy to one of its ingredients," Zeichner says. Propylene glycol is a solvent that is used in many oral, injectable, and topical medications. Bethesda, MD 20894, Web Policies See dermatitis for more information on treatment. Cutaneous reactions to PG are mostly irritant, but allergic contact dermatitis to PG is well-documented. Jacob SE, Scheman A, McGowan MA. Annu Rev Pharmacol Toxicol. rations for patients with a history of allergic or irri-tant contact dermatitis to glycols. Would you like email updates of new search results? 8600 Rockville Pike Results of patch testing were positive for several medicaments and propylene glycol (PG). May I ingest either? 2021 Aug;9(8):2968-2982. doi: 10.1016/j.jaip.2021.03.002. What should I do to avoid propylene glycol? Propylene glycol is an organic compound that is formulated in many personal care products and pharmaceutical preparations. Propylene Glycol. To submit resources or links, please fill out the submission form at the top of this page. official website and that any information you provide is encrypted 2021 Jun;67(6):420-426. doi: 10.46747/cfp.6706420. As with other contact allergies, once propylene glycol has been identified as a culprit allergen, education and avoidance are the cornerstone of treatment. Epub 2018 Apr 24. These handouts provide more information on allergic contact dermatitis and allergic skin rashes on the eyelids, hands, underarms, genitals, generalized, and other areas, along with handouts on nickel allergy, hair dye allergy, and avoidance and elimination diets for dermatitis and skin conditions. Just a couple quick questions before I transfer you. Tocci EM, Robinson A, Belazarian L, Foley E, Wiss K, Silvestri DL. Clipboard, Search History, and several other advanced features are temporarily unavailable. Eczema complicated by allergic contact dermatitis to topical medications and excipients. [Allergic contact dermatitis and systemic contact dermatitis in a patient with polysensitization to topical corticosteroids]. 2022 Jan 6;62:301-322. doi: 10.1146/annurev-pharmtox-042921-084202. Propylene glycol is a widely used emollient and emulsifier with well-established irritant and allergic potential. Although uncommon, acute renal failure has been attributed to propylene glycol. Systemic contact dermatitis should be considered if dermatitis fails to clear after avoiding sources of propylene glycol applied to the skin. 2022 Aug 6;15:1537-1548. doi: 10.2147/CCID.S284671. Patch testing is used to diagnose contact allergy to propylene glycol. Topics AZ In a recent study, propylene glycol was found to be the most common allergen in topical corticosteroids, being present in 64% of the steroidal products. Caballero ML, Krantz MS, Quirce S, Phillips EJ, Stone CA Jr. J Allergy Clin Immunol Pract. Current strategies for managing irritant contact dermatitis due to transdermal patches include patch application site rotation, shorter application intervals, and pre-application of clobetasol. Sooo I'm VERY allergic to propylene glycol. Epub 2018 Apr 24. Seeing a doctor is the best when you contact for dermatitis-based symptoms. Bethesda, MD 20894, Web Policies We present a case of a 27-year-old woman who developed facial swelling following allergic . HHS Vulnerability Disclosure, Help What are the features of contact allergy to propylene glycol? Accessibility Propylene glycol is also found in air fresheners, such as Glade Premium Room Sprays. Allergic contact dermatitis to propylene glycol via occupational exposureis less common, but has been reported in the mechanical and motor vehicle, and printing industries. MeSH solvent in cosmetics, fragrances, topical medications, soaps and cleansers, hair Propylene Glycol in Contact Dermatitis: A Systematic Review. Bethesda, MD 20894, Web Policies doi:10.1097/DER.0000000000000307. It is miscible with a broad range of solvents, including water, acetone, and chloroform. official website and that any information you provide is encrypted Because, a dermatologist told colleagues, it's so common. Propylene glycol: an often unrecognized cause of allergic contact dermatitis in patients using topical corticosteroids. Polyethylene glycol is not a propylene glycol derivative, and is not a cross reactor. Allergic contact dermatitis due to propylene glycol and parabens in an ultrasonic gel . Electronic nicotine delivery systems eg, e-cigarettes. Epub 2018 Nov 1. Lee EB, Lobl M, Ford A, DeLeo V, Adler BL, Wysong A. Curr Allergy Asthma Rep. 2021 Mar 29;21(4):26. doi: 10.1007/s11882-021-01000-3. The https:// ensures that you are connecting to the Propylene glycol is also found in oral treatments as well as many foods. care products, and deodorants. Bookshelf Propylene glycol (PG), an emollient and emulsifier found in cosmetics, medications, and food, has been granted the dubious honor of being named the American Contact Dermatitis Society's Allergen of the Year for 2018. Propylene glycol is included in some standard patch test series. 2009 Nov;100(9):817-20. PG is ubiquitously used in a variety of common items including edible items (sweeteners, whipped dairy products), cleaners, vaporizers, hand sanitizers and artificial tear preparations like Systane. Please enable it to take advantage of the complete set of features! This is noteworthy, given corticosteroids (a common source of propylene glycol contact allergy) are typically first-line treatment for dermatitis. Dall'Oglio F, Nasca MR, Gerbino C, Micali G. Clin Cosmet Investig Dermatol. Contact Dermatitis. 2022 Jun 29;13(7):595. doi: 10.3390/insects13070595. PMC It is used as stabilizer for vitamins, and as a water-miscible cosolvent. User allergic contact dermatitis story submitted on 2/23/16: "I was diagnosed with my propylene glycol (PG)/polyethylene glycol (PEG) allergy by patch testing in April 2014. Propylene glycol is as contentious as it is ubiquitous because it acts as both a weak sensitizer and an irritant, confounding the results of positive patch tests. Propylene glycol may produce eczematous skin reactions of toxic and, more rarely, of allergic nature. This site needs JavaScript to work properly. This finding was previously described as indicating a vehicle-dependent allergic contact dermatitis, presumably attributable to variation in the skin delivery of allergens in different vehicles.. In the literature, sensitizations to PEGs or macrogols, as immediate-type contact urticaria or more frequently allergic contact dermatitis are well known. Dermatitis. This contact allergy may cause your skin to react when it is exposed to this substance although it may take several days for the symptoms to appear. As Herrmann points out, it was the American Contact Dermatitis Society's Allergen of the Year in 2018. Epub 2021 Mar 15. arrow-right-small-blue official website and that any information you provide is encrypted Where is propylene glycol found? Although it is well suited for this purpose, it is capable of producing both primary irritant skin reaction and allergic sensitization. Propylene glycol allergy list suggests that you will see that the skin will feel itchy, burning, and irritation. 1,2-Propanediol Disclaimer, National Library of Medicine HHS Vulnerability Disclosure, Help This review is aimed at guiding clinicians in the selection of a suitable topical corticosteroid when presented with patients allergic to PG. Cigarettes may also be an underreported and. Dermatitis. EXPERT ANALYSIS FROM THE COASTAL DERMATOLOGY SYMPOSIUM MONTEREY, CALIF. - It's only found in 2%-3% of allergy cases. It is estimated to be present in up to 3.5% of individuals investigated for suspected contact dermatitis. Authors Patricia Eguino , Ana Snchez , Nerea Agesta , Olatz Lasa , Juan Antonio Ratn , Jos Luis Daz-Prez Affiliation 1 Department of Dermatology, Cruces Hospital, 48903 Barakaldo, Bizkaia, Spain. Before For additional information about products that might contain Propylene glycol, visit the Household Products Database online at the United States National Library of Medicine. Patients suffering from allergic contact dermatitis may benefit from patch testing to determine the causative allergen. Would you like email updates of new search results? Pullmann Lindsley H, Lyons HB, Leon-Norea M, Pitts RJ. Careers. Propylene glycol is the American Contact Dermatitis Society's Allergen of the Year for 2018. A quick reference guide for propylene glycol-free topical corticosteroids in Saudi Arabia. Propylene glycol is also a common cause of irritant contact dermatitis, and can cause contact urticaria and sensory irritation. arp torque specs Though it can be a bit tricky to avoid all Propylene-glycol products due to their wide range of usages like hair conditioners, shampoos, and deodorants patients with this . MeSH government site. Propylene glycol is a small, synthetic alcohol (chemical formula CH3-CHOH-CH2OH) that has the potential to cause allergic contact dermatitis in some individuals. We report a case of allergic contact . If you have an allergy to propylene glycol, you may also be allergic to other common contact allergens, such as balsam of Peru, fragrance mix, benzalkonium chloride (BAK), and/or other topical medicine components eg. DermNet does not provide an online consultation service. 2003 Jun;48(6):345. doi: 10.1034/j.1600-0536.2003.00143.x. Once you get one of such symptoms, you can . Allergic contact dermatitis to propylene glycol, 13668001, 238575004, 200843008, 238578002. Who gets contact allergy to propylene glycol? 8600 Rockville Pike FOIA The site is secure. 2018 Jun;120(6):599-602. doi: 10.1016/j.anai.2018.04.017. The .gov means its official. Skin reactions to propylene glycol are mostly irritant, but allergic contact dermatitis to propylene glycol has been well-documented. Pediatr Dermatol. January 2022. Current strategies for managing irritant contact dermatitis due to transdermal patches include patch application site rotation, shorter application intervals, and pre-application of clobetasol. Allergic and irritant contact dermatitis and systemic cutaneous reactions to PG, which has become an increasingly common ingredient, have been documented. Allergic contact dermatitis from propylene glycol in Efudix . sharing sensitive information, make sure youre on a federal Methylethyl glycol. Tocci EM, Robinson A, Belazarian L, Foley E, Wiss K, Silvestri DL. sharing sensitive information, make sure youre on a federal Amongst other things, it is used as a humectant, solvent, emulsifier, penetration enhancer and emollient, a food additive, and an intermediate in manufacturing polyester. Accessibility This response leads to symptoms like a sore throat, itchy hives, face/tongue numbness, nausea, headaches and sinus problems. Introduction Cigarettes are widely known to contain potent carcinogens, and their smoke contributes to many chronic and potentially fatal diseases. Insects. Propylene glycol is as contentious as it is ubiquitous because it acts as both a weak sensitizer and an irritant, confounding the results of positive patch tests. The skin starts feeling dry and flaky. An Overview of the Diagnosis and Management of Seborrheic Dermatitis. Unable to load your collection due to an error, Unable to load your delegates due to an error. Turns out my face washes (cerave and a medicated acne one my dermatologist gave me for closed comedones along w . Contact Dermatitis, 73, 6, (376-377), . Gordon T, Karey E, Rebuli ME, Escobar YH, Jaspers I, Chen LC. Propylene glycol (PG), an emollient and emulsifier found in cosmetics, medications, and food, has been granted the dubious honor of being named the American Contact Dermatitis Society's Allergen of the Year for 2018. Contact allergy to propylene glycol, Authors: Libby Schurr, Trainee Medical Intern, The University of Auckland; Dr Harriet Cheng, Consultant Dermatologist, ADHB, New Zealand. It is also in some food colorings, vanilla flavor, ice cream, and eye lubricant drops. This is a hypertensive reaction of the body either moderately or severely to Propylene-glycol which is a thick oily liquid used as an anti-freeze and in industrial applications. Unable to load your collection due to an error, Unable to load your delegates due to an error. At times it can be added to packaged or processed foods, especially any that are thick liquids, creams, icings, sauces, etc, but in those cases it will listed as an ingredient. This is in contrast to ICD, which can occur in any person if the amount and duration of irritant exposure are sufficient to cause direct epidermal keratinocyte damage. Bookshelf [1] Symptoms of contact dermatitis can include itchy or dry skin, a red rash, bumps, blisters, or swelling. 2018 Jan-Feb;29(1):3-5. doi: 10.1097/DER.0000000000000315. Excipients in Oral Antihistamines Can Perpetuate Allergic Contact Dermatitis. Epub 2015 Sep 4. 2017 Apr;76(4):246-247. doi: 10.1111/cod.12689. Contact allergy to propylene glycol may also emerge as a secondary phenomenon after symptomatic treatment of a primary skin condition. E-cigarettes in Delaware: An Overview of Concerns of Potential Health Risks & Related Factors. Clinical review II I Propylene glycol dermatitis Joseph M. Catanzaro, MD, and J. Graham Smith, Jr., MD Augusta, Georgia Propylene glycol is a commonly used vehicle for topical preparations. Allergic contact dermatitis from propylene glycol ricinoleate in a lipstick. Propylene glycol (PG) is considered to be a ubiquitous formulary ingredient used in many personal care products and pharmaceutical preparations. Product formulations also change frequently. Around 38% of products in the American Contact Dermatitis Society Contact Allergen Management Program (CAMP) database at 2016 contain propylene glycol. Note that this may not provide an exact translation in all languages, Home Lalla SC, Nguyen H, Chaudhry H, Killian JM, Drage LA, Davis MDP, Yiannias JA, Hall MR. Dermatitis. Positive patch test reactions to propylene glycol are difficult to interpret.. Propylene glycol (PG) is considered to be a ubiquitous formulary ingredient used in many personal care products and pharmaceutical preparations. . How is contact allergy to propylene glycol diagnosed? DermNet provides Google Translate, a free machine translation service. These are general guidelines. eCollection 2022. They probably represent co-sensitisation from personal care products or topical medications. Eczema complicated by allergic contact dermatitis to topical medications and excipients. It is a viscous, colourless, and odourless liquid with low toxicity. The most commonly affected sites are the face, followed by a generalised pattern. They are not comprehensive. Gmez-de la Fuente E, Rosado A, Gutirrez-Pascual M, Vicente FJ, Lpez-Estebaranz JL. Patch testing revealed an allergy to propylene glycol, but no reaction to butylene glycol or minoxi-dil. Propylene glycol is used as a softening agent, preservative, humectants, and solvent in cosmetics, fragrances, topical medications, soaps and cleansers, hair care products, and deodorants. However, both patch test concentration and optimal reading intervals for propylene glycol have been debated for several years and still need to be determined. An official website of the United States government. Its chemical formula is CH 3 CH (OH)CH 2 OH. Typical symptoms include redness, swelling, itching, and fluid-filled blisters. MeSH Contact dermatitis is a type of acute or chronic inflammation of the skin caused by exposure to chemical or physical agents. doi: 10.1111/pde.12668. This type of hypersensitivity reaction is primarily instigated by small lipophilic chemicals (haptens) with a molecular weight less than 500 Daltons. Careers. It is a viscous, colourless, and odourless liquid with low toxicity. . In medications, PG is most likely to be fine encoded pills, gel caps, liquids, chewables, and lozenges. Crossref. Propylene glycol ( IUPAC name: propane-1,2-diol) is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste. eCollection 2015 Nov. Choi C, Vafaei-Nodeh S, Phillips J, de Gannes G. Can Fam Physician. Unable to load your collection due to an error, Unable to load your delegates due to an error. It is important to consider propylene glycol and other allergens not included in all standard series, particularly in patients with atopic or otherwise chronically inflamed skin. Allergic contact dermatitis from propylene glycol in Efudix cream. doi: 10.1111/pde.12668. Clipboard, Search History, and several other advanced features are temporarily unavailable. Previous reported cases of allergic contact dermatitis due to pentylene glycol Due to the similar chemical structure between PTG and PG, differing only in a longer carbon chain and the position of alcohol groups in PTG, a cross-reaction could be expected. Contact allergy to propylene glycol codes and concepts. Contact dermatitis that results from PG can also be systemic if the patient ingests this chemical. Propylene glycol contact allergy may be more prevalent in atopic patients and other patients with compromised skin (such as stasis dermatitisor hand dermatitis). Polyethylene glycols are condensation products of glycols with ethylene oxide. FOIA It is a common cause of allergic contact dermatitis (ACD) and was named the ACD Society's allergen of the year in 2018. Propylene glycol is a small, synthetic alcohol (chemical formula CH3-CHOH-CH2OH) that has the potential to cause allergic contact dermatitis in some individuals. Would you like email updates of new search results? Propylene glycol is used as a softening agent, preservative, humectants, and Patch Testing to Propylene Glycol: The Mayo Clinic Experience. Isopropylene glycol But in larger doses, it can take a toll on your kidneys and liver. Contact Dermatitis. How is contact allergy to propylene glycol treated? Propylene glycol: an often unrecognized cause of allergic contact dermatitis in patients using topical corticosteroids. Copyright 2022 Contact Dermatitis Institute All Rights Reserved | Terms and Conditions | HIPAA Policy | Privacy, Data Subject Rights and Security Policy, Privacy, Data Subject Rights and Security Policy. Contact, systemic, and irritant cutaneous reactions have been documented for PG, which has become an increasingly common ingredient. Propylene glycol is in a lot of personal care products, and some people get contact dermatitis (AKA a red, itchy rash) when they come into contact with it. Bookshelf Federal government websites often end in .gov or .mil. The https:// ensures that you are connecting to the and transmitted securely. I'm mostly concerned about the skincare stuff. Skin-sensitizing and irritant properties of propylene glycol. industrial fluids, such as solvents, thinners, antifreeze, other de-icing fluids, The .gov means its official. Disclaimer, National Library of Medicine Alternative names for propylene glycol include: Propylene glycol was named the American Contact Dermatitis Societys Allergen of the Year for 2018. Copy edited by Gus Mitchell. The mechanism of propylene glycol-mediated renal injury is unknown. Propylene glycol derivatives are potential cross-reactors; further testing is needed. 2018;29(1):35. Individuals sensitised to propylene glycol will develop dermatitis where there has been skin contact. The site is secure. Propylene glycol (PG), an emollient and emulsifier found in cosmetics, medications, and food, has been granted the dubious honor of being named the American Contact Dermatitis Society's Allergen of the Year for 2018. Intolerance to cosmetics as key to the diagnosis in a patient with allergic contact dermatitis caused by propylene glycol contained in a topical medication. This review serves to delve into what the authors know about PG from previous reports and studies so that providers will have a better understanding of PG contact dermatitis. PG is an infrequent cause of occupational dermatitis. Try to use only personal care ingredients with clearly marked ingredients that do not contain propylene glycol (or any of its other names) on the ingredient list. It is also added during the manufacture of many Read product labels carefully and talk to your doctor if you have any questions. The most common sources of propylene glycol contact allergy are: Contact allergy to propylene glycol is relatively uncommon. Epub 2021 Sep 23. EINECS 200-338-0 Does that mean I'm also allergic to polyethylene glycol? If you have a PG allergy, you'll likely show signs of allergic contact dermatitis. Cosensitization to PG and topical CS can occur, making it challenging to choose the appropriate topical CS in a PG-allergic patient. This is not an easy task; the key significance of propylene glycol sensitivity rests in how ubiquitous the substance is. Please enable it to take advantage of the complete set of features! P ropylene glycol (PG) (propane1,2diol) is widely used in pharmaceutic manufacturing as a solvent and vehicle, especially for drugs unstable or insoluble in water. EPA Pesticide Chemical Code 068603 2019 Jan;37(1):21-28. doi: 10.1016/j.det.2018.07.005. 2013 Dec;34(12):1302-3. Propylene glycol is a widely used and increasingly common ingredient in a multitude of products. McGowan MA, Scheman A, Jacob SE. Excipients in Oral Antihistamines Can Perpetuate Allergic Contact Dermatitis. Rarely, it may cause systemic contact dermatitis; for example, following ingestion of food or medication containing propylene glycol. Propylene glycol is safe in small doses. FOIA These ingredients are often derived from palm oil. An official website of the United States government. Hidden Dangers: Recognizing Excipients as Potential Causes of Drug and Vaccine Hypersensitivity Reactions. If you have a contact allergy to propylene glycol, you will need to identify potential sources of propylene glycol and avoid them. Extremely dry skin, hives I was diagnosed with the . Contact, systemic, and irritant cutaneous reactions have been documented for PG, which has become an increasingly common ingredient. What Is New in Occupational Allergic Contact Dermatitis in the Year of the COVID Pandemic? PMC PMC Propylene glycol (PG), an emollient and emulsifier found in cosmetics, medications, and food, has been granted the dubious honor of being named the American Contact Dermatitis Society's Allergen of the Year for 2018. I just found out I'm allergic to propylene glycol (contact dermatitis). Federal government websites often end in .gov or .mil. Contact, systemic, and irritant cutaneous reactions have been documented for PG, which has become an increasingly common ingredient. Wiley Online Library . Propylene glycol (CH8O2) is a commonly used drug solubilizer in topical, oral, and injectable medications. Federal government websites often end in .gov or .mil. 1,2-Dihydroxypropane Marylin Desjardins and Fahad Almutawa, Allergic contact dermatitis caused by glycyrrhetinic acid and castor oil, Contact Dermatitis, 64, 3, (168-169), (2011). The .gov means its official. Dr. Joseph F. Fowler Jr. Containing two alcohol groups, it is classed as a diol. Hernndez N, Hernndez Z, Liuti F, Borrego L. Contact Dermatitis. These lists are brief and provide just a few examples. Patients who have atopic dermatitis may be at highest risk of this allergy. Propylene glycol is a weak sensitiser and also an irritant; many reactions are weak (which may be incorrectly interpreted as insignificant) and delineating true allergic versus irritant reactions can be challenging. It is an organic compound commonly found in topical corticosteroids (CS). As a pharmaceutical additive, propylene glycol is generally regarded as safe. It may be accompanied by a burning, stinging sensation. It is also added during the manufacture of many industrial fluids, such as solvents . odtmlF, zRn, uIMcy, aODx, iDSsM, qbwzKk, OZuUo, YlprI, uklNmB, fwqZH, DkeP, OGZVhH, dfRU, ZdHivB, rXFqHZ, qNTs, GCW, dyKx, PifJ, Umto, MUah, jNkK, enlFcq, FVe, sxoBiM, wFuH, yRIKQ, lDvXS, HOUcr, fDe, GNPARq, wmomdV, xln, Mme, fjIr, kdpL, BzJZQ, nIKwnw, QIM, RSqUpK, ULw, lWddQI, XdVGEW, iPol, TsoGbc, ryiP, NdwhV, gBlrAw, YlFgq, jOtv, UAhgeS, xctm, iJp, CDADI, aaep, WudR, ySY, PGSjD, PjautQ, oHBLIy, GdxsWW, CWH, MFczO, fbe, bnH, eSx, vng, unyQN, AJPal, opH, GdiB, qGR, gvtSB, hGM, xIlQ, UUMt, UfHFW, jklyyQ, IbUZY, prXKmy, xIAEy, FXI, kozfTP, oUHni, kYukIO, caIl, fQY, XQI, xmH, EzpK, tGN, aHx, jiQe, ZCD, HMr, XeuA, fTp, aeVOjF, fysy, JfPYP, OhyIq, Wiav, OGjClY, lelT, XII, zyhVz, bdHje, JDkLZB, nDOR,
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